High Affinity, Developability and Functional Size: The Holy Grail of Combinatorial Antibody Library Generation
نویسندگان
چکیده
منابع مشابه
High affinity, developability and functional size: the holy grail of combinatorial antibody library generation.
Since the initial description of phage display technology for the generation of human antibodies, a variety of selection methods has been developed. The most critical parameter for all in vitro-based approaches is the quality of the antibody library. Concurrent evolution of the libraries has allowed display and selection technologies to reveal their full potential. They come in different flavor...
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ژورنال
عنوان ژورنال: Molecules
سال: 2011
ISSN: 1420-3049
DOI: 10.3390/molecules16053675